A 11-year-old female was referred with a progressive decrease of vision in the right eye for the past two months. Slit lamp evaluation of the anterior segment was within normal limits except for iris coloboma in the inferior nasal quadrant of each eye.
Dilated fundus examination showed optic disc and retinochoroidal coloboma in both eyes and juxtapapillary choroidal neovascularization with intraretinal hemorrhage in the right eye (arrow).
Fundus fluorescein angiography of the right eye showed the hyperfluorescence of the choroidal neovascular membrane located at the edge of the coloboma.
Optical coherence tomography passing through the choroidal neovascular membrane revealed the hyperreflective material with subretinal fluid.
Ocular coloboma is a congenital anomaly represented by missing pieces of tissue in the eye structure that appear as notches or gaps in the iris, retina, choroid, or optic nerve. Choroidal coloboma is a developmental anomaly occurring from incomplete embryonic fissure closure. Associated findings include microphthalmia, cataract, retinal detachment and rarely choroidal neovascularization.
Credit: Kemal Tekin, M.D., from Ulucanlar Eye Training and Research Hospital
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