Frosted branch angiitis associated with chickenpox infection

A twelve-year-old boy presented with complaining of sudden visual loss in both eyes. His past medical history revealed a chickenpox infection 20 days prior to presentation. Visual acuity was 20/800 in each eye. External exam was unremarkable. Slit lamp exam of the anterior segment showed no KPs with 1+ anterior chamber cells in left eye.  Dilated fundus examination revealed diffuse vascular sheathing in veins bilaterally.

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OCT demonstrated corresponding macular edema with serous retinal detachment.

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Fundus fluorescein angiography showed optic disc hyperfluorescence, venous staining, increased tortuosity and mild leakage which were prominent in the left eye.

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Patient was considered as frosted branch angiitis associated with chickenpox infection.

The clinical presentation of frosted branch angiitis does not correlate with any single etiology. It is a rare entity that has a broad differential diagnosis including noninfectious and infectious etiologies such as leukemia -lymphoma, auto-immune conditions, herpes simplex virus, varicella zoster virus, and toxoplasmosis.

 

Credit: Merve İnanç Tekin, MD, FEBO

Ulucanlar Eye Training and Research Hospital, Ankara, Turkey

Instagram accounts: @uveacademy and @merveinanctekin

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